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Sex steroid concentrations in the plasma of 24-day pregnant Mongolian gerbils (Meriones unguiculatus) and their male and female fetuses were measured using radioimmunoassays. It was found that, on Day 24 of gestation: (a) androgen levels were higher in those male fetuses developing adjacent to no female fetuses than in those male fetuses developing between two female fetuses and (b) androgen levels were higher in those female fetuses developing between two male fetuses than in those female fetuses with no immediate, male neighbours. Further, plasma taken from 24-day pregnant dams that had exhibited vaginal opening at a relatively early age had significantly lower androgen levels and significantly higher estradiol levels than did plasma taken from 24-day pregnant dams that had exhibited relatively late vaginal opening. The data provide direct evidence of hormonal mediation of previously described differences both in the morphology and reproductive biology of male and female adult gerbils as a function both of their fetal intrauterine locations relative to members of the other sex and of the age at vaginal introitus of their respective dams
Adult female mice. --- Adult. --- Age. --- Androgen. --- Behavior. --- Biology. --- Contiguity. --- Estradiol. --- Female. --- Fetal sex steroids. --- Fetuses. --- Function. --- Gerbil. --- Gerbils. --- Gestation. --- Hormonal. --- Intrauterine position. --- Level. --- Life. --- Male. --- Maternal sex steroids. --- Meriones unguiculatus. --- Meriones-unguiculatus. --- Mongolian gerbil. --- Mongolian gerbils. --- Mongolian-gerbil. --- Morphology. --- Neonatal androgen. --- Plasma. --- Proximity. --- Radioimmunoassay. --- Rats. --- Sex ratio. --- Sex. --- Sexes. --- Sexual maturation. --- Steroid-hormones. --- Steroid. --- Time. --- Unguiculatus. --- Uterine position.
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Examining data describing the sex composition of 1074 Caesarean-delivered litters of house mice, 253 Caesarean-delivered and 265 vaginally delivered litters of Mongolian gerbils, and 854 vaginally delivered litters of golden hamsters, we determined whether segregation of sexes between uterine horns and correlations between litter size and litter sex ratio were present in each of the three rodent species studied. Although significant deviations from expected distributions of male and female fetuses were found, these deviations from chance were not the same in any two of the three species examined. Analyses also indicated that the correlation between litter size and litter sex ratio that Huck, Seger, and Lisk (1990) found in vaginally delivered infant hamsters is present in vaginally delivered infant Mongolian gerbils, but not in their Caesarean-delivered colony mates. In gerbils, and perhaps hamsters as well, the correlation between litter size and litter sex ratio appears to be a result of sex-biased perinatal mortality correlated with litter size rather than of sex-biased conception correlated with litter size
Behavior. --- Birth. --- Colonies. --- Female mongolian gerbils. --- Female. --- Fetuses. --- Gerbil. --- Gerbils. --- Golden hamster. --- Golden-hamster. --- Golden-hamsters. --- Hamster. --- Hamsters. --- Horns. --- House mice. --- Infant. --- Litter sex ratio. --- Litter size. --- Male. --- Meriones-unguiculatus. --- Mice. --- Mongolian gerbil. --- Mongolian gerbils. --- Mongolian-gerbil. --- Mortality. --- Mouse. --- Perinatal. --- Rodent. --- Sex ratio. --- Sex. --- Sexes. --- Size. --- Time. --- Uterine position.
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Medical genetics --- Genetic engineering --- Human reproductive technology --- Fetus --- Ethics, Medical --- Genetics, Medical --- Moral and ethical aspects --- Abstracts --- Ethics, Medical. --- Fetus. --- Genetics, Medical. --- -Human reproductive technology --- -Medical genetics --- -#GROL:MEDO-241.63*5<01> --- #GROL:SEMI-241.63*2 --- Clinical genetics --- Diseases --- Heredity of disease --- Human genetics --- Medical sciences --- Pathology --- Genetic disorders --- Assisted human reproduction --- Assisted conception --- Conception --- Human assisted reproduction --- Human reproduction --- Medical technology --- Reproductive technology --- Designed genetic change --- Engineering, Genetic --- Gene splicing --- Genetic intervention --- Genetic surgery --- Genetic recombination --- Biotechnology --- Transgenic organisms --- Human Genetics --- Medical Genetics --- Genetics, Human --- Anthropology, Physical --- Chromosome Disorders --- Sex Chromosome Disorders --- Genetic Diseases, Inborn --- Molecular Medicine --- Fetal Tissue --- Fetuses --- Mummified Fetus --- Retained Fetus --- Fetal Structures --- Fetal Structure --- Fetal Tissues --- Fetus, Mummified --- Fetus, Retained --- Structure, Fetal --- Structures, Fetal --- Tissue, Fetal --- Tissues, Fetal --- Embryo, Mammalian --- Fetal Research --- Medical Ethics --- Medicine --- Professionalism --- Bioethics --- -Abstracts --- Genetic aspects --- Technological innovations --- ethics --- #GROL:MEDO-241.63*5<01> --- Moral and ethical aspects&delete& --- Assisted human reproductive technology --- Human assisted reproductive technology --- Medical genetics - Moral and ethical aspects - Abstracts --- Genetic engineering - Moral and ethical aspects - Abstracts --- Human reproductive technology - Moral and ethical aspects --- Fetus - bibliography --- Ethics, Medical - bibliography --- Genetics, Medical - bibliography
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